Session 4: Knee II
Onsdag den 25. oktober
11:00-12:00
Lokale: Reykjavik
Chairmen: Lasse Enkebølle Rasmussen og Anders Odgaard
34. Outcome of tibial component valgus subsidence in cementless Oxford unicompartmental knee replacement
Lasse E. Rasmussen, Thomas Lind-Hansen, Claus Varnum, Per Wagner Kristensen
Orthopedic Dept. , Sygehus Lillebælt, Vejle Hospital; Orthopedic Dept., Sygehus Lillebælt, Vejle Hospital; Orthopedic Dept., Sygehus Lillebælt, Vejle Hospital; Orthopedic Dept., Sygehus Lillebælt, Vejle Hospital
Background: We shifted from the cemented to the
cementless Oxford unicompartmental knee
replacement (OUKR) in January 2015 to
reduce the risk of cementing errors and
mistaken revision from radiolucent lines.
Upon the change we experienced a number
of tibial fractures and tibial component
subsidence. In September 2015 we altered
our surgical technique, by gently tapping
down the tibial component and moving the
vertical cut as lateral as possible, to ensure
the largest possible component.
Purpose / Aim of Study: To investigate if the new surgical approach
altered the occurrence of tibial component
subsidence and, in the case of subsidence,
to investigate the 1-year outcome.
Materials and Methods: We performed a prospective intervention
study. X-rays were taken postoperatively at
4 weeks and 1 year for all cementless
OUKR operated in 2015 and 2016. 1 year
after surgery, all patients were interviewed
regarding satisfaction. Results were
compared before and after the intervention.
Findings / Results: Subsidence occurred within 4 weeks in
42/187 women and 28/166 men.
Subsidence before September 2015; 28/105
= 27%. After September 2015; 42/250 =
17%; (p =0,037). The tibial component
subsided within the first 4 weeks; hereafter
it remained stabile for the following 11
months in 49 (98%) of the cases. 38
patients (78%) were extremely satisfied, 8
(16%) were satisfied, and 4 (8%) were less
satisfied. Two of the less satisfied patients
were due to neuroma formation. The level of
satisfaction was similar in patients before
and after the intervention in September
2015.
Conclusions: Valgus subsidence of the tibial component
in cementless OUKR may depend on the
surgical technique. It may occur within the
first 4 weeks postoperatively whereafter the
component stabilizes. Valgus subsidence
does not seem to affect patient-reported
outcome 1 year postoperatively.
35. The perioperative infection rate in total knee arthroplasty may be dependent on season
Hannes Torngren, Sara Kamilla Clausen, Anders Odgaard, Thomas Lind
Orthopaedic department, Gentofte Hospital; Orthopaedic department, Gentofte Hospital; orthopaedic department, Gentofte Hospital; orthopaedic departmento, Gentofte Hospital
Background: Total knee arthroplasty (TKA) is a surgical
procedure routinely performed, primarily as
end-stage treatment for osteoarthritis,
resulting in approximately 8000 primary
procedures every year in Denmark. While
many aspects of causes and risk factors for
infections and TKAs have been extensively
examined, none have, to the authors’
knowledge, sufficiently explored\r\nthe
relationship between seasonality and risk of
perioperative infections
Purpose / Aim of Study: We performed a retrospective study to
determine the rate of revision due to deep
infection, defined as those revised within the
first 2 year, for each month of the year . The
aim of the study was to investigate wether
there is a variation in infection rate after
primary TKA based on the month the
primary surgery was done
Materials and Methods: The study was based on a large dataset
from the national Danish Knee Arthroplasty
Registry (DKR). We received data on a total
of 124.484 procedures and set out to
identify all patients who, between January
1st 1997 and December 31st 2014, had
undergone primary TKA resulting in revision
surgery due to infection. The revision rate
and relative risk for infection for each month
were calculated and analyzed with
Pearsons chi-square test.
Findings / Results: The revision rate due to infection was
calculated for each season. Of procedures
performed during summer, 1,02% ended in
revision due to infection. In comparison, the
remainder of the seasons had revision rates
of 0,73% (fall), 0,82% (winter) and 0,80%
(spring) (P = 0.013) The relative risiko
between summer vs the rest was 1.31 [95%
CI, 1.10 - 1.55]
Conclusions: The relative risk of revision surgery due to
infection is 1.31 times higher if the primary
TKA surgery is performed during the
summer months compared to the remainder
of the year. The reason for the increased
infection rate is yet to be determined
36. Treatment of Osteoarthritis with the Stromal Vascular Fraction of Abdominal Adipose Tissue - a Pilot Study
Kristoffer Weisskirchner Barfod, Lars Blønd
Dept. of Orthopedic Surgery, Zealand University Hospital; Dept. of Orthopedic Surgery, Zealand University Hospital
Background: Treatment of knee osteoarthritis (OA) with minimally
manipulated cell therapies have gained increasing
popularity. The stromal vascular fraction of
abdominal Adipose tissue (SVF) is a rich source of
mesenchymal stem cells. Studies using SVF have
shown promising results.
Purpose / Aim of Study: To investigate the feasibility and safety issues of
treatment of knee OA with intra-articular injection with
SVF harvested and prepared using the Lipogems
System.
Materials and Methods: The study was performed as a prospective
cohort study with follow up after 3, 6 and 12
months. Primary endpoint was any adverse
event at 3 months. Secondary endpoint was
KOOS. Patients aged 18-70 years were eligible
for inclusion if they had been diagnosed with
osteoarthritis. Exclusion criteria were
malalignment of the knee > 5 degrees, instability
or BMI > 35.
SVF was harvested through two stab incision just
below the umbilicus and prepared for implantation
using the Lipogems system; an enzyme-free
technology that works through a mild mechanical
tissue cluster size reduction. Implantation of 8-
16ml SVF in the knee was performed using a 21
gauge syringe.
Findings / Results: 20 patients were included and 19 participated in
follow up. Mean (SD) age was 49 (9), weight 89kg
(22), height 170cm (23). One adverse event was
registered as a patient complaint of cosmetically
changes to the abdominal subcutaneous tissue. 13
of 19 would go for the procedure again. At 3 months
KOOS Pain increased 9 (p=0.003) points, Symptoms
4 (p=0.197), ADL 9 (p=0.008), Sport 13 (p=0.002)
and QOL 15 (p=0.008). Differences dropped to
border significant values at 6 and 12 months.
Conclusions: Treatment of knee OA with intra-articular injection
with SVF harvested and prepared using the
Lipogems System is feasible and safe. Efficiency of
the treatment is questionable and is not evaluated in
the present study.
37. Patients with anteromedial osteoarthritis achieve the greatest improvement in patient reported outcome after total knee arthroplasty
Iben Rønne Jessing, Mette Mikkelsen, Kirill Gromov, Henrik Husted, Thomas Kallemose, Anders Troelsen
Clinical Orthopaedic Research Hvidovre, Hvidovre Hospital; Clinical Orthopaedic Research Hvidovre, Hvidovre Hospital; Clinical Orthopaedic Research Hvidovre, Hvidovre Hospital; Clinical Orthopaedic Research Hvidovre, Hvidovre Hospital; Clinical Orthopaedic Research Hvidovre, Hvidovre Hospital; Clinical Orthopaedic Research Hvidovre, Hvidovre Hospital
Background: The osteoarthritic (OA) disease pattern of
the knee is one of the determinants for
choice of arthroplasty concept when knee
replacement is indicated, but whether the
disease pattern has a direct effect on
postoperative outcome has not previously
been investigated.
Purpose / Aim of Study: The aim was to investigate if different OA
disease patterns and severity of
osteoarthritis had an effect on postoperative
outcome after receiving total knee
arthroplasty (TKA).
Materials and Methods: 472 patients with complete pre- and 1-year
postoperative patient reported outcome
measures (PROM's) undergoing TKA
surgery from January 2013 to November
2015 at one hospital were retrospectively
identified and classification of the OA
disease pattern were made on preoperative
full weight bearing radiographs. During the
investigated period no partial knee
replacements were performed and
measured resection was the universal
technical approach. The outcome was
development in PROM scores from pre- to
1-year postoperatively.
Findings / Results: The key findings showed the greatest
improvement in mean PROM scores for
anteromedial OA (AMOA) compared with
other OA disease patterns; 3.2 points (95 %
confidence interval (CI) 1.5-4.9, p < 0.001)
in Oxford Knee score, 8.2 points (95 % CI
2.6-18.9, p = 0.135) in Forgotten Joint score
and 0.08 points (95 % CI 0.02-0.14, p =
0.002) in EQ-5D score. Similar results were
observed favoring bone-on-bone AMOA
compared with AMOA that had only partial
thickness cartilage loss.
Conclusions: Patients classified with AMOA achieve
greater improvement in PROM scores after
TKA surgery compared with other OA
disease patterns. This finding has important
implications for reporting, risk stratification
and interpretation in TKA outcome studies,
including randomized trials.
38. Limited use of the orthopaedic surgeon’s advice on non-surgical treatment for knee osteoarthritis – An observational cohort study.
Sofie Ryaa, Lina H. Ingelsrud, Søren T. Skou, Ewa M. Roos, Anders Troelsen
Department of Orthopaedic surgery, Copenhagen University Hospital Hvidovre; Department of Orthopaedic surgery, Copenhagen University Hospital Hvidovre; Department of Sports Science and Clinical Biomechanics AND Department of Physiotherapy and Occupational Therapy, University of Southern Denmark AND Næstved-Slagelse-Ringsted Hospitals; Research Unit for Musculoskeletal Function and Physiotherapy, Department of Sports Science and Clinical Biomechanics, University of Southern Denmark; Department of Orthopaedic surgery, Copenhagen University Hospital Hvidovre
Background: The Good Life with osteoArthritis in
Denmark (GLA:D) programme consists of
patient education and supervised exercise
therapy and adheres to clinical guidelines
for knee osteoarthritis (OA). Non-operative
treatments like GLA:D may be beneficial
when surgery is not considered timely.
Purpose / Aim of Study: To present the clinical course of action
taken by patients advised to participate in
GLA:D by an orthopaedic surgeon before
deciding on undergoing knee replacement.
Materials and Methods: Patient records from all patients with knee
OA consulting one orthopaedic surgeon in
2015 were reviewed to detect those being
advised GLA:D participation. Radiologic OA
was classified with Kellgren-Lawrence (KL)
grade 0-4, none-severe. Results after 3
months were extracted from the GLA:D
database, including a visual analogue scale
(VAS) for knee pain (0-100, best-worst), and
the Knee injury and Osteoarthritis Outcome
score knee-related quality of life (QOL)
subscale (0-100, worst-best).
Findings / Results: Out of 142 patients with primary referrals
due to knee OA, 83 (58.5%) were advised
to participate in GLA:D. They had a mean
(SD) age of 65.0 (10.7) and 59 (62.8%)
were female. They were either not eligible
for surgery, or pending surgical decision and
34 (44.8%) had a KL grade 3-4. Only 18
(22%) patients participated in GLA:D, and
14 (17%) completed 3 months follow-up.
For these patients, the mean (SD) VAS pain
score improved from 61.4 (18.6) to 42.7
(25.1) (p<0.001), while knee-related QOL
remained unchanged (from 41.5 (16.2) to
43.8 (12.3) (p=0.535)).
Conclusions: The majority of patients did not follow the
surgeon’s advice on non-surgical treatment.
In those who did the significant pain
reduction found indicates patient education
and supervised exercise therapy being
beneficial in patients prior to deciding on
knee replacement, or if surgery is not
indicated.
39. Using wearable sensors to determine knee range of movement in knee arthroplasty patients. A pilot study.
Mie Christina Hansen, Rasmus Malik Thaarup Høegh, Jacob Fyhring Mortensen, Helge Bjarup Dissing Sørensen, Anders Odgaard
Ortopædkirurgisk afdeling, Herlev-Gentofte Hospital, Gentofte; Department of Electrical Engineering, Technical University of Demark (DTU); Ortopædkirurgisk afdeling, Herlev-Gentofte Hospital, Gentofte; Department of Electrical Engineering, Technical University of Demark (DTU); Ortopædkirurgisk afdeling, Herlev-Gentofte Hospital, Gentofte
Background: Range of motion (ROM) under specific
activities may be related to patients'
experience of the quality of knee function. It
may be superior compared to measurements
of passive ROM in an ambulatory.
Purpose / Aim of Study: The objective of this study is to investigate and
develop a new method to determine dynamic
knee function using wearable sensors.
Materials and Methods: 35 subjects aged 60-75 were included in the
study. They met 1 of 3 criteria: Healthy (normal
functioning knee), pre-operative or 3 months
post-operative. We used 2 sensors with a
magneto-, accelero- and gyrometer that
measure the angle between the femur and
tibia. With 2 sensors taped to the skin, patients
performed 2 exercises; walk on treadmill 2
km/h and individually chosen fast pace. For
reproducibility the exercises were carried out
twice.
Findings / Results: Significant difference in knee function between
the 3 groups was found. Subjects with healthy
knee had significant higher active ROM (mean
= 53.6°), angular velocity and acceleration
than the 2 other groups. The post-operative’s
active ROM (mean = 43.4°) were significantly
higher than the pre-operative group (mean =
37.4°), but the angular velocity and
acceleration were not significantly different
from the pre-operative group. Retests showed
the method to be highly reproducible. The
largest difference between the groups was
observed when instructed to walk at a fast
pace.
Conclusions: The sensors measures of dynamic ROM
were reproducible and consistent with the
degree of pathology. This method is simple
and allows gait analysis to be telemetric in
the patient's daily life, and it thus
fundamentally differs from costly laboratory
tests. The method can be used to monitor
patients both pre- and postoperatively.
Further studies will investigate whether the
application of machine learning on the data
can predict Oxford Knee Score.
40. Isolated Tibial Insert Exchange after Primary Total Knee Arthroplasty
Amir Pasha Attarzadeh, Amin Bakhtyar Baram, Thorbjørn Gantzel Christiansen, Thomas Lind
Orthopedic department, Herlev og Gentofte Hospital; Orthopedic department, Herlev og Gentofte Hospital; Orthopedic department, Herlev og Gentofte Hospital; Orthopedic department, Herlev og Gentofte Hospital
Background: Patients with Total Knee Arthroplasty (TKA) can be
revised with isolated polyethylene liner exchange.
The indication varies from pain, stiffness, recurrent
effusion, wear or instability. The effectiveness of this
procedure is quite controversial. An analysis of
results based on these subgroups may give us
knowledge about the best indication.
Purpose / Aim of Study: The aim of this study is to evaluate the results of
isolated polyethylene exchange in patients with
instability and pain.
Materials and Methods: From out database we identified all patients who
underwent revision of a TKA with liner exchange in
our institution in the period from 2010 to 2013. We
included all patients with instability and pain as
described by the surgeon. We excluded all patients
who had other interventions.
Patient reported outcome was evaluated with a
KOOS and a Oxford Knee Score questionnaire and
clinical assessment was conducted using Knee
Society Score.
Findings / Results: We had a population of 19 patients, 12 women and
7 men. One patient had bilateral liner exchange.
Mean increase in liner thickness was 5,8mm (2,5-
7,5mm). Mean follow-up time after revision was 44
months (30-60).
Mean KOOS for categories Pain, other Symptoms
and ADL was 62-64 but for Function in Sport and
Recreation and for Quality of Life it was 27 and 43.
Mean Knee Society Score and Function score was
66 and 69. Mean Oxford Knee Score was 29.
Postoperatively, mean VAS in rest was 1 and in
activity 4.
Average time between the operations was 24
months.
Conclusions: Our results reveal poor outcome when isolated
polyethylene liner exchange is performed on the
indication instability and pain. Careful patient
selection for this procedure may yield better results.
Further studies are needed to confirm this.