Session 15: Shoulder /
Elbow
Fredag d. 26. oktober
11:00-12:00
Lokale: Reykjavik
Chairmen: Lars Henrik Frich og Thomas Falstie Jensen
116. Diabetes Mellitus affect the Prognosis of Frozen Shoulder: a prospective, multicentre 2-year follow-up study of 235 cases
Per Hviid Gundtoft, Mikkel Lindegaard Attrup, Anne Krog Kristensen, Jette Wessel Vobbe, Per Hölmich, Lilli Sørensen
Ortopedic Department, Kolding Sygehus; Sports Orthopaedic Research Centre-Copenhagen , Copenhagen University Hospital Amager-Hvidovre; Orthopedic Department, Vejle Hospital; Orthopedic Department, Vejle Hospital; Sports Orthopaedic Research Centre-Copenhagen , Copenhagen University Hospital Amager-Hvidovre ; Orthopedic Department, Vejle Hospital
Background: Patients with diabetes mellitus are often referred to
as having a worse prognosis of a frozen shoulder,
but the evidence for this statement is non-existent.
Purpose / Aim of Study: To study if diabetes mellitus affects the severity of a
frozen shoulder prognosis.
Materials and Methods: In this 2-year follow-up study patients from three
participating hospitals with newly diagnosed
frozen shoulder were consecutively included and
asked to fill out a questionnaire: at time of
diagnosis and at 6-, 12- and 24-months follow-
up. The questionnaire included the Oxford
Shoulder Score (OSS) and the Visual Analogue
Scale (VAS) for both maximum and average
daily pain. Furthermore, patients were asked to
report on whether arthroscopic release had been
performed. Diabetes mellitus status was
recorded for all patients, and patients not
previously diagnosed with diabetes mellitus were
invited to be tested with the HbA1c test.
Findings / Results: A total of 235 patients were included, of which 34
were previously diagnosed with frozen shoulder.
Patients with diabetes mellitus had similar OSS
(p=0.22) and VAS score for maximum (p=0.46)
and average (p=0.46) daily pain at time of
diagnosis compared to patients without diabetes
mellitus. Both groups improved in OSS and VAS
score, but patients with diabetes mellitus had a
worse OSS at 6- (p=0.04), and 24-months follow-
up (p=0.02); worse VAS score for maximum daily
pain at 6- (p=0.04), 12- (p=0.03) and 24-months
follow-up (p=0.03); and worse VAS score for
average daily pain at 6- (p=0.02), and 12-months
follow-up (p=0.01)
Patients with diabetes mellitus had an increased
probability of undergoing arthroscopic release
(p<0.05).
Conclusions: Diabetes mellitus is associated with a worse
prognosis in patients with frozen shoulder, but all
patients can expect gradual improvement during the
2 years following their diagnosis.
117. Quantitative analysis of F18-FDG uptake in the shoulder for the diagnosis of frozen shoulder (adhesive capsulitis)
Linus Daniel Leonhard Duchstein, Lars Friberg, Lene Rørdam, Line Marker, Mads Okholm, Michael Rindom Krogsgaard
Department of Clinical Physiology and Nuclear Medicine, Bispebjerg and Frederiksberg Hospital; Department of Clinical Physiology and Nuclear Medicine, Bispebjerg and Frederiksberg Hospital; Department of Clinical Physiology and Nuclear Medicine, Bispebjerg and Frederiksberg Hospital; Section for sportstraumatology M51, Bispebjerg and Frederiksberg Hospital; Section for sportstraumatology M51, Bispebjerg and Frederiksberg Hospital; Section for sportstraumatology M51, Bispebjerg and Frederiksberg Hospital
Background: Frozen shoulder is characterized by
pain and reduced mobility of the
shoulder caused by inflammatory
contracture of the joint capsule
leading. Clinical diagnosis is based on
movement restriction, but in the first
phase of the condition motion can be
normal and the condition can be
interpreted as impingement syndrome,
which does not involve the shoulder
capsule and which is treated
differently.
Purpose / Aim of Study: Since inflammation/increased tissue
turnover is present in frozen shoulder
we aimed to study whether 18F-FDG
accumulation in the joint during a
PET/CT scan could distinguish frozen
shoulder from impingement.
Materials and Methods:
Ten consecutive patients with frozen
shoulder and 10 with subacromial
impingement scheduled for
arthroscopic treatment underwent F18-
FDG PET/CT before surgery (200MBq,
1h rest).
PET/CT slides were evaluated visually
by 2 experienced nuclear medicine
physicians and quantitatively by
defining regions of interest (ROI)
around both shoulders and analyzing
the standard uptake values (SUV). The
other shoulder was used for
normalization. All analyses very done
blinded to patient group.
Findings / Results: Patients with frozen shoulder show
increased SUV uptake evaluated
visually and by ROI analysis. The
kappa-value for the visual evaluation
was 0.74. There was a sensitivity of
85% and specificity of 93% for
physicians evaluation and 77%
sensitivity and 96% specificity for the
quantitative analysis. Combining these
two methods sensitivity was 100%
sensitivity and specificity 92%.
Conclusions: 18F-FDG PET/CT is a sensitive and
non-invasive method to diagnose
frozen shoulder and distinguish it from
subacromial impingement. This
method is relevant in cases where
there is doubt about the diagnosis
frozen shoulder.
118. Bone mineral density changes of the proximal humerus and functional outcomes after 3- and 4 part fractures treated with an angle stable locking plate.
Elisabeth Bright, Sebastian Breddam Mosegaard, Torben Bæk Hansen, Thomas Klebe, Michael Toft Væsel, Inger Mechlenburg, Maiken Stilling
Department of Orthopaedic Surgery, Aalborg University Hospital; University clinic for Hand, Hip and Knee Surgery, Regional Hospital Holstebro; University clinic for Hand, Hip and Knee Surgery, Regional Hospital Holstebro; Section for Shoulder and Elbow Surgery , Center for Planned Surgery, Regional Hospital Silkeborg; Department of Orthopaedic Surgery, Regional Hospital Viborg; Orthopaedic Research Unit, Department of Clinical Medicine , Aarhus University Hospital; Department of Orthopaedics; Department of Clinical Medicine, Aarhus University Hospital
Background: Osteoporosis is often present in
displaced proximal humeral fractures and
challenges joint preserving surgery.
Little is known of functional outcome in
relation to osteoporosis and stress
shielding after surgery with an angle
stable locking plate (ASLP).
Purpose / Aim of Study: To investigate bone mineral density
(BMD) changes in the proximal humerus
(PH) and functional outcomes 1 year
after fractures treated with ASLP.
Materials and Methods: 36 patients (29 female) at mean 66 years
(range 38-83) with unilateral 3-4-part
PH fractures were included in a
prospective multicenter study. Patients
were operated with Winsta ASLP
(Fischer-Medical). A 1 year follow-up
included repeated measurements of
shoulder BMD (primary outcome). Function
was measured with Constant Score (CS)
and the Western Ontario Osteoarthritis
of the Shoulder index (WOOS), quality of
life with the Short Form 36 (SF-36), and
pain was reported by VAS. The effect of
T-scores above and below the
osteoporosis limit (-2.4) was investigated.
Findings / Results: At 1 year, the %-change in BMD was
higher in the operated (-18%) versus
healthy (-6%) PH in all patients
(p=0.01). 17 (47.2%) patients had a
T-score below -2.4, but T-scores had no
measurable effect on functional
outcomes. From 3 to 12 months the SF-36
physical component score decreased
(p=0.02) and increased in pain (p=0.03),
while the CS increased 11.71 points, 95%
CI [8.51–14.92]. VAS pain and WOOS were
similar pre-injury and at 1 year
follow-up (p=0.17).
Conclusions: 1 year after plating of dislocated
proximal humerus fractures BMD
measurements showed stress shielding in
the proximal humerus. No significant
difference in pain and shoulder function
was found pre-injury compared to 1 year
post-operatively, but the general
function (SF-36) decreased. Osteoporosis
status did not affect outcomes.
119. Revision rate of shoulder arthroplasty for proximal humerus fracture sequelae. A register-based study from The Nordic Arthroplasty Register Association.
Ditte Unbehaun, Sigrid Rasmussen, Inger Mechlenburg, Jeppe Vejlgaard Rasmussen
Department of Orthopaedic Surgery, Aarhus University Hospital; Department of Orthopaedic Surgery, Aarhus University Hospital; Department of Orthopaedic Surgery, Aarhus University Hospital; Department of Orthopaedic Surgery, Herlev University Hospital
Background: There is no consensus on the optimal treatment of
proximal humerus fracture (PHF) sequelae.
Purpose / Aim of Study: The primary aim of this study was to report the
revision rate of shoulder arthroplasty for PHF
sequelae and to report the reasons for revision. The
secondary aim was to determine the revision rate for
stemmed hemiarthroplasty (SHA) and reverse
shoulder arthroplasty (RSA).
Materials and Methods: Data was derived from the Nordic Arthroplasty
Register Association. Kaplan-Meier was used to
illustrate the 10-year survival rates. Cox regression
model was used to calculate hazard ratios. Age
categories, gender, period of surgery and
arthroplasty type were included in the model.
Findings / Results: 19,857 primary arthroplasties were reported from
2004 to 2013, of which 1,563 (8%) were operated
due to PHF sequelae. 175 (11.2%) arthroplasties
were revised. The most common reasons for
revision were luxation/instability (3.9%), others,
which include glenoid wear (2.4%) and infection
(1.7%). The cumulative arthroplasty survival rate
was significantly higher for SHA compared to RSA
(p=0.006). The cumulative arthroplasty survival
rates after 1, 5 and 10 year were 0.96, 0.89 and
0.86 for SHA and 0.89, 0.85 and 0.85 for RSA. The
adjusted hazard ratio of revision of RSA relative to
SHA was 1.73 (CI: 1.23;2.45). The cumulative
arthroplasty survival rate was significantly higher for
female patients compared to male patients
(p<0.001). The cumulative arthroplasty survival
rates after 1, 5 and 10 year were 0.95, 0.89 and
0.87 for female patients and 0.91, 0.82 and 0.75 for
male patients. The adjusted hazard ratio of revision
of male patients relative to female patients was 1.80
(CI: 1.27;2.55).
Conclusions: Patients treated with RSA compared to patients
treated with SHA and male patients compared to
female patients had an increased risk of revision.
120. Risk factors for revision and patient-reported outcome after treatment with shoulder arthroplasty for proximal humerus fracture sequelae. A follow-up study from the Danish Shoulder Arthroplasty Registry
Sigrid Rasmussen, Ditte Unbehaun, Inger Mechlenburg, Alexander Amundsen, Jeppe Vejlgaard Rasmussen
Department of Orthopaedic Surgery, Aarhus University Hospital; Department of Orthopaedic Surgery, Aarhus University Hospital; Department of Orthopaedic Surgery, Aarhus University Hospital; Department of Orthopaedic Surgery, Herlev University Hospital; Department of Orthopaedic Surgery, Herlev University Hospital
Background: Fracture sequelae is challenging to treat in shoulder
reconstruction.
Purpose / Aim of Study: The purpose of this study was to investigate risk
factors for revision and patient-reported outcome
after treatment with shoulder arthroplasty for
previously non-operatively treated proximal humerus
fracture sequelae.
Materials and Methods: Data from the Danish Shoulder Arthroplasty Registry
included 837 shoulder arthroplasties performed for
fracture sequelae between 2006 and 2015. Western
Ontario Osteoarthritis of the Shoulder index (WOOS)
was used to evaluate patient-reported outcome at
one year. Type of arthroplasty, gender, age,
indication of treatment and period of surgery was
investigated as risk factors. Cox regression and
linear regression were used in the statistical
analyses.
Findings / Results: 644 patients treated with stemmed hemiarthroplasty
(SHA) and 127 patients treated with reverse
shoulder arthroplasty (RSA) were included. During a
mean follow-up of 3.7 years, 48 (7%) SHA and 14
(11%) RSA were revised. Men treated with RSA had
a significant higher revision rate (HR=3.81, 95%CI:
1.12; 12.93, p=0.03) than men treated with SHA.
454 (54%) of the patients returned a complete
WOOS. The mean WOOS-score was 47.4 for SHA
and 47.5 for RSA. Patients older than 65 years had
a significant lower WOOS-score (mean
difference=-6.64, 95%CI:-12.24;-1.04, p=0.02) than
patients younger than 65 years.
Conclusions: Shoulder arthroplasty for fracture sequelae is
associated with a poor patient-reported outcome and
a high risk of revision. Especially men treated with
RSA had a high risk of revision. Older patients had a
statistically significant lower WOOS-score compared
to elderly patients, but the difference did not exceed
the minimal clinically important difference.
121. Cost-Utility Analysis Of Operative Versus Nonoperative Treatment Of Displaced Midshaft Clavicular Fractures
Anne-Kathrine Rosenkrans Sørensen, Lianna Hede Hammeken, Andreas Haubjerg Qvist, Steen Lund Jensen, Lars Ehlers
Department of Business and Management, Danish Center for Healthcare Improvements, Aalborg University; Department of Business and Management, Danish Center for Healthcare Improvements, Aalborg University; Department of Orthopaedic Surgery, Aalborg University Hospital; Department of Orthopaedic Surgery, Aalborg University Hospital; Department of Business and Management, Danish Center for Healthcare Improvements, Aalborg University
Background: Conventional treatment of displaced
midshaft clavicular fractures is
nonoperative. Recent studies have
implied that operative treatment might
result in a faster return to work,
resulting in a decreased productivity
loss for society. The cost-utility of
operative versus nonoperative
treatment has not previously been
investigated utilizing a societal
perspective.
Purpose / Aim of Study: To assess the cost-utility of plate
fixation compared with nonoperative
treatment of displaced midshaft
clavicular fractures in Danish adults.
Materials and Methods: Decision analytic modelling of
incremental costs and quality adjusted
life years (QALYs) was applied. Data
was primarily retrieved from a recent
Danish randomized controlled trial
(RCT), published RCT’s and field
observation. A one-year time horizon
was applied and prices reported in
2016-level. A health sector and a
societal perspective were applied.
Findings / Results: Operative treatment is associated with
a larger gain in QALYs and a higher
cost compared to nonoperative
treatment. The incremental cost
effectiveness ratio (ICER) was
estimated to DKK 1,273,455 per QALY
from a health sector perspective and
DKK 1,241,364 per QALY from a
societal perspective. Considering a
subgroup of patients with a high-load
shoulder profession, operative
treatment result in a lower gain in
QALYs and a higher cost compared to
nonoperative treatment from a health
sector perspective. Considering a
societal perspective, the ICER was
estimated to DKK -1,100,927 per
reduction of one QALY. Sensitivity
analyses showed that all results were
subject to uncertainty.
Conclusions: Operative treatment is not cost-
effective considering a threshold of
£30,000 (≈ DKK 267,600) per QALY
as reported by NICE. However, for
patients with a high-load shoulder
profession, operative treatment might
be cost-effective considering
productivity costs.
122. Shoulder Impingement: Improving the quality of treatment in the primary sector.
Ahmed Halloum, Haubjerg Qvist Andreas, Rasmeussen Deutch Søren
Ortopædkirurgisk afd., Regionshospitalet Viborg; Ortopædkirurgisk afd., Aalborg Universitetshospital; Ortopædkirurgisk afd., Regionshospitalet Rander
Background: In 2013, the Danish Health Authority released
national guidelines describing the treatment of
impingement patients in the primary sector,
along with guidelines for specialist referral.
Despite this, we see a growing number of
patients referred without initial relevant
treatment in the primary sector.
Purpose / Aim of Study: To improve the quality of treatment in the
primary sector by informing the general
practitioners (GP) about the existence of the
national guidelines.
Materials and Methods: We conducted a pre and post
interventional study. In April 2017 a letter
was sent to all GPs in our service area
informing about the National treatment
Guidelines. In the period of September to
November 2016 and June to November
2017 journals were reviewed to determine
the quality of treatment in primary care.
Patients were divided into three groups of
three months: Pre-intervention (PI), early
post intervention (EPI) and late post
intervention (LPI). Relevant primary care
treatment was defined as minimum three
months of relevant physiotherapy and
corticosteroid treatment. Treatment in the
outpatient clinic was used as a surrogate
marker for the quality of treatment in
primary care.
Findings / Results: 260 patients (135 F, 125 M) with at mean age
of 56 years were included in the study. In the
PI group 22 patients (20 %) were offered
surgery versus 20 patients (33 %) in the EPI
group and 20 patients (22 %) in the LPI group.
There was no significant difference before and
after our intervention (PI vs. EPI: p=0,068 and
PI vs. LPI: p=0,73)
Conclusions: Our intervention did not improve the quality of
treatment of impingement patients in the
primary sector. Raising awareness of the
National Guidelines is difficult on a single
hospital level, and may require national effort.