Session 16: Pediatrics
Fredag d. 26. oktober
11:00-12:00
Lokale: Sweden
Chairmen: Line Kjeldgaard Petersen og Niels Wisbech Petersen
123. The effectiveness of instrumented gait analysis for interdisciplinary interventions in young children with cerebral palsy – a randomised controlled trial
Anders Mätzke Rasmussen, Søren Overgaard, Lars Kjaersgaard Hansen, Ulrike Dunkhase-Heinl, Yanko Petkov, Vilhelm Engell, Niels Wisbech Pedersen, Anders Holsgaard-Larsen
The Orthopaedic Research Unit, Department of Clinical Research, University of Southern Denmark, Odense, Denmark; The Orthopaedic Research Unit, Department of Clinical Research, University of Southern Denmark, Odense, Denmark; H.C. Andersen Children’s Hospital, Odense University Hospital, Odense, Denmark; Department of Paediatrics, Lillebaelt Hospital, Kolding, Denmark; Department of Paediatrics, Hospital of Western Jutland, Esbjerg, Denmark; The Orthopaedic Research Unit, Department of Clinical Research, University of Southern Denmark, Odense, Denmark; The Orthopaedic Research Unit, Department of Clinical Research, University of Southern Denmark, Odense, Denmark; The Orthopaedic Research Unit, Department of Clinical Research, University of Southern Denmark, Odense, Denmark
Background: The Cerebral Palsy follow-Up Program (CPUP) is
used to ensure consistent examinations of children
with cerebral palsy (CP). However, gait function by
3D gait analysis is not evaluated within CPUP.
Purpose / Aim of Study: To test the hypothesis that improvements in gait and
function following interdisciplinary interventions
using 3D gait analysis in the decision-making are
superior to those following ‘care as usual’ without
gait analysis in young children with CP.
Materials and Methods: A pragmatic, single blind, randomised (1:1)
controlled trial. Primary outcome was gait function at
52 weeks follow-up evaluated by Gait Deviation
Index (GDI) and secondary outcomes were: patient
reported outcomes of function, disability and quality
of life.
Using a minimum clinically important difference of
7.9 (SD 12) GDI points, alpha = 0.05, and 80%
power, a total of 60 children were included.
Findings / Results: Between-groups change scores were evaluated
by a multiple regression model. The statistical
analysis plan was registered at ClinicalTrails.gov
(NCT02160457) and a protocol paper was
published ahead.
Sixty children (median age 6y11m) with CP at
Gross Motor Function Classification System
levels I (n = 42) and II (n = 18), were randomised
to interventions with or without gait analysis. The
categories of interventions were dominated by
non-surgical interventions that were applied in 36
to 86% of the participants.
No significant or clinically relevant between-
group differences in change scores of the
primary or secondary outcomes were found.
Conclusions: Interdisciplinary interventions using gait analysis did
not improve gait or function in the present sample of
relatively young and well-functioning children with
CP. However, 3D gait analysis may still be relevant
in children with higher levels of disability or if a
functional diagnosis is needed.
124. Retrograde Femoral Nailing Through an Open Physis Does Not Impair Growth in Pigs
Ahmed Abdul-Hussein Abood Abood, Ole Rahbek, Morten Lykke Olesen, Bjørn Borsøe Christensen, Bjarne Møller-Madsen, Søren Kold
Children's Orthopedics and Reconstruction, Aalborg University Hospital; Children's Orthopedics, Aarhus University Hospital; Orthopedic Research Lab, Aarhus University Hospital; Orthopedic Research Lab, Aarhus University Hospital; Children's Orthopedics, Aarhus University Hospital; Children's Orthopedics and Reconstruction, Aalborg University Hospital
Background: The use of retrograde femoral
intramedullary nails in children for deformity
correction is controversial. It is unknown if
the injury to the central part of the growth
plate results in premature bony union,
leading to limb deformities or discrepancies.
Purpose / Aim of Study: The aim of this study is to asses physeal
healing and bone growth after insertion of a
retrograde femoral nail in a skeletally
immature experimental porcine model.
Materials and Methods: Eleven immature pigs were included in the
study. One leg was randomised for
operation with a retrograde femoral nail
(diameter 10 mm), whilst the non-operated
contralateral remained as control. All nails
were inserted centrally in coronal and
sagittal plane under fluorescence, and the
nails spanned the physis. The nails were
removed at 8 weeks. Both femora in all
animals underwent MRI at baseline (pre-
operatively), 8 weeks (after nail removal)
and 16 weeks (before euthanasia). Femoral
bone length was measured at 5 sites
(anterior, posterior, central, lateral and
medial) using 3d T1-weighted MRI. Growth
was calculated after 8 weeks (growth with
nail) and 16 weeks (growth without nail).
Corresponding 95% confidence intervals
were calculated. Operated side was
compared to non-operated. One animal died
at 8 weeks and was only subject to 8 week-
analysis.
Findings / Results: No differences in axial growth were
observed between operated and non-
operated sides. Mean growth difference was
0,61 mm [-0,78;2,01] whilst the nail was
inserted into the bone and 0,72 mm
[-1,04;1,65]; after nail removal.
Furthermore, no signs of angular bone
deformities were found when comparing
operated side to non-operated side. No
premature bony healing at the physis
occurred.
Conclusions: The insertion of a retrograde femoral nail
through the centre of an open physis might
be a safe procedure with no growth arrest.
125. The development in frature incidence in children 1980-2014
Andreas Vestergaard Larsen, Esben Mundbjerg, Jens Martin Lauritsen, Christian Færgemann
Dept of Orthopedics and Traumatology, OUH; Dept of Orthopedics and Traumatology, OUH; Dept of Orthopedics and Traumatology, OUH; Dept of Orthopedics and Traumatology, OUH
Background: Previous Scandinavian studies have
shown an increase in the incidence of
paediatric fractures over the past 60
years. So far no Danish study has
aimed to describe the development of
incidence rates of paediatric fractures.
Purpose / Aim of Study: To describe the long-time development
in the incidence rates of paediatric
fractures and to describe the frequency
of the most common fractures.
Materials and Methods: A retrospective register study of all
paediatric bone fractures 0-15 years
inhabited in the Odense Municipality
and treated at Odense University
Hospital 1980-2014. Data was
extracted from the patient registration
system and stratified by gender and
age groups.
Findings / Results: The study included 32,927 children
aged 0-15 with fractures. Overall 58 %
were boys and the median age was 11
years for both boys and girls. The peak
age in males was 13 years throughout
the study period, whereas a tendency
of declining peak age was found in
girls from 11 years of age in 1980 to 10
years of age in 2014. The incidence
rate was 330 (95% CI: 304-358) per
100,000 patient-years for boys and
258 (95% CI:226-274) per 100,000
patient-years for girls. The highest
incidence rate was found in the age
group 12-15 years and the lowest in
the age group 0-1 years in both boys
and girls. The incidence rate increased
steadily until the age of 13 years for
boys and 11 years for girls. Hereafter
the incidence rate decreased rapidly.
The overall incidence rate declined
23.4 % in in the study period as boys
and girls contributed equally to the
decline. The most common fracture
was that of the distal radius/forearm
with 28.5 %.
Conclusions: The present study does support the
findings in previous studies. Our study
showed a significant decline in the
incidence rate of pediatric fractures in
a 35 years period 1980-2014. Boys
and girls contributed equally to the
decline.
126. Accelerated Ponseti method is an effective treatment for Congenital Clubfoot
Vilhelm Engell, Mathias Bünger, Ole Rahbek, Søren Ege
Ortopaedic department, Aarhus University Hospital; Ortopaedic department, Aarhus University Hospital; Ortopaedic department, Aarhus University Hospital; Rehabilitation, Aarhus University Hospital
Background: The Ponseti method (PM) is the gold
standard in the treatment of Congenital
Clubfoot. We report our results and
experience with accelerated Ponseti
method(APM) in a consecutive
prospective series of clubfeet.
Purpose / Aim of Study: In APM the rate of manipulation and
casting is twice or three times a week
thus reducing the time to correction
Materials and Methods: In this consecutive prospective series
we included all clubfeet treated with
APM at the department in 2016.
Controls were clubfeet treated with PM
in 2015 and Follow-up was at 1 year
Findings / Results: APM reduced the manipulation and
casting time by 40 % from 32 to 19
days (P=0,0002).Tendo Achilles
Lenghtening (TAL) was performed in
28 clubfeet (97 %) in APM and 25
clubfeet (89 %) in PM (P=0,3525).No
skin problems in any of the groups
During follow-up we had two patients
(10%) relapse with tightness of the
dorsiflexion in both groups (P=1). All
were treated with (re)casting and a
second TAL
Conclusions: All feet were corrected with the APM.
The rate of relapse with the APM is not
higher than in clubfeet treated with the
PM.
This is preliminary results, with a short
follow-up. We note the reduction in
time to correction is significant and
consider APM safe.
127. Comparison of direct and indirect measurements of pulse in the proximal femoral epiphysis using an intracranial pressure monitoring probe
Gottliebsen Martin, Mathias Bünger, Ahmed Abdul-Hussein Abood, Vilhelm Engell, Ole Rahbek
Ortopædkirurgisk Afdeling E, Århus Universitetshospital; Ortopædkirurgisk Afdeling E, Århus Universitetshospital; Ortopædkirurgisk Afdeling , Aalborg Universitetshospital; Ortopædkirurgisk Afdeling E, Århus Universitetshospital; Ortopædkirurgisk Afdeling E, Århus Universitetshospital
Background: Open reduction surgery of severe cases of slipped
capital femoral epiphysis (SCFE) guided by an
intracranial pressure (ICP) monitoring probe
inserted in the femoral head is a promising new
technique. It has also been proposed to do closed
reduction (CR) of acute SCFE (the condition that
carries the highest risk of avascular necrosis) aided
by monitoring pulse in the femoral head using ICP
probes inserted through cannulated screws.
However, little is known about the actual relationship
between different approaches to monitor pulsatile
flow in the femoral head.
Purpose / Aim of Study: To compare direct and indirect techniques for
monitoring pulse in the femoral head in an
experimental animal model.
Materials and Methods: Animal model using anesthetized pigs with an
immature femoral head. Perfusion of the femoral
head was confirmed by a preoperative gadolinium
MRI scan. The following measurements were
performed using the Codman ICP probe on 9 hip
joints; direct measurement using 1.5 mm drill hole
and indirect measurements through joint aspiration
cannula, 4.5 mm cannulated screw and 6.5 mm
cannulated screw. Direct measurements were
performed through a drill hole in the adjacent
metaphysis.
Findings / Results: Pulsatile flow was observed on all measurements.
Groups were tested using ANOVA. Pressure was
significantly higher using the direct approach (31.6
mmHg) to the femoral head compared to indirect
techniques (6.7 - 13.7 mmHg). We were unable to
find any difference between the different indirect
techniques.
Conclusions: Indirect monitoring through cannulated screws may
have a limited role for CR of acute SCFE. Because
of the more reliable direct monitoring technique we
advocate that CR is only undertaken in a setting
where conversion to surgical dislocation and direct
monitoring of pulse in the femoral head can
performed.
128. The effects of rotation on radiological parameters in the Spine.
christian wong, Johanna Hall, Kasper Gosvig
Dept of Orthopedics, hvidovre hospital; Dept of Radiology, hvidovre hospital; Dept of Radiology, h
Background: Vertebral rotation in straight spines or in
spines with small scoliosis may potentially
affect measurement of radiological parameters
in both the frontal and sagittal plane. This is
important, since it could lead to potential
misdiagnosis of scoliosis and other clinical
consequences, and until now, this has not
been examined.
Purpose / Aim of Study: To examine the effect of axial vertebral rotation
of the spine on measurement of common
radiological parameters.
Materials and Methods: Reconstructions from computed
tomography scans of 40 consecutive
included and anonymized patients with
straight spines or small scoliosis. Fourteen
sagittal and coronal reconstructions
covering the whole pelvis and spine were
executed. Radiographic parameters in both
the frontal and sagittal plane were
measured blinded and separately by three
doctors. These parameters were evaluated
for inter-rater reliability using intra-class
correlation coefficient and mixed model
analysis for the effects of rotation. The
parameters were also analyzed sub-
stratified according to ‘Lenke’s
classification’ and 15 sub-categories of
thoracic and lumbar Cobb’s angle.
Findings / Results: Vertebral rotation in general does not have any
significant effects in both the frontal and
sagittal plane. However, there are significant
effects on lumbar and spinopelvic radiologic
parameters in moderate to extreme rotation or
for larger scoliosis. Interrater reliability was
very good to good.
Conclusions: In conclusion, axial spinal rotation does not
influence common radiological parameters in
the frontal and sagittal plane, except in cases
of extreme rotation or large scoliosis for
selected parameters, thus this does not lead to
potential misinterpretation in scoliosis
diagnosis, treatment or research.
129. Testing a new surgical principle of guided growth for correction of rotational deformity of long bones in childhood.
Andreas Balslev-Clausen, Peter Buxbom, Christian Wong, Klaus Hindsø
Dept. of Orthopaedics, Hvidovre Hospital; Dept of Orthopaedics, Herlev Hospital; Dept. of Orthopaedics, Hvidovre Hospital; Dept. of Orthopaedics, Rigshospitalet
Background: Correction using osteotomies and plates or frames
for angular and rotational deformities of the lower
extremity are large surgical procedures with risk of
complications, but they can be necessary for
amending the subsequent gait disturbances, pain
and decreased function caused by the deformity.
Guided growth are used for correcting angular
deformities in the growing pediatric patients, but the
technique have not been used for rotational
deformities in humans. So far only animal studies
have been published.
Purpose / Aim of Study: To investigate, if derotation using guided growth is
possible in the human pediatric population.
Materials and Methods: Five children (9 bone segments) with symptomatic
rotational deformities were included after informed
consent in a prospective and consecutive cohort.
Using intraoperative fluoroscopy, Pediplates® were
inserted across the growth plate in a 45 degree (dg.)
angle on both sides of either the femoral and/or
tibial physes of the knee. RSA beads were inserted
systematically, and patients were followed up every
three months with radiostereometric analysis.
Findings / Results: At 9.3 months follow up, there was an avg. of 5.5
dg. of derotation (range 0-12 deg) and a longitudinal
growth of 8.4 mm (range 2.8-13). However, the first
two patients (4 segments) showed minimal
derotation and growth after 6 months, whereas the
later three patients (5 segments) showed an
average rotation of 9.3 dg. and 9.4 mm of growth.
Also, a rebound effect of 2.49 dg. was demonstrated
in two children 9.9 months after plate.
Conclusions: The principles of guided growth can be applied for
rotational deformity in growing children. In principle,
this can be utilized to correct rotational deformities
with minimal morbidity and discomfort. Exact plate
placement of plates is crucial and a rebound effect is
to be expected.