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· DOS Abstracts

Association between comorbidity and post-oper-

ative health-related quality of life in total hip ar-

throplasty patients

Eva Natalia Glassou, Alma Becic Pedersen, Peter Kloster Aalund, Torben Bæk

Hansen

University clinic of hand, hip and knee surgery, Department of Orthopedic Sur-

gery, Regional Hospital West Jutland; Department of Clinical Epidemiology, Aar-

hus University Hospital; University clinic of hand, hip and knee surgery, Depart-

ment of Orthopedic Surgery, Regional Hospital West Jutland; University clinic

of hand, hip and knee surgery, Department of Orthopedic Surgery, Regional

Hospital West Jutland

Background:

By reducing pain and improving hip function, a total hip arthro-

plasty (THA) improves the health related quality of life (HRQol). However, us-

ing patient reported outcome measures, approximately 10% of patients report

some degree of dissatisfaction after surgery. The pre- operative comorbidity

burden may play a role in predicting THA patients with little or no benefit of a

THA.

Purpose / Aim of Study:

We examined whether the post-operative patient

reported HRQol measured with the EQ-5D at 3 and 12 month of follow-up was

dependent of the comorbidity burden in THA patients treated due to osteoar-

thritis.

Materials and Methods:

THA patients treated at the Regional Hospital West

Jutland from September 2008 to December 2013 formed the basis for the

study. Comorbidity burden was measured with the Charlson Comorbidity Index

(CCI). Pre- surgery hospital history for all patients was collected using an ad-

ministrative database. Patients were divided into three groups; no comorbidity

burden, low comorbidity burden (CCI 1-2) and a high comorbidity burden (CCI

3+). Patient reported HRQol was measured using the EQ-5D pre-operative and

at 3 and 12 month follow-up. Analysis were carried out with multiple linear re-

gressions and adjusted for age and gender.

Findings / Results:

In total 1,582 THA patients were included (86%). A posi-

tive association between comorbidity burden and HRQoL was found at 3 month

follow up for THA patients with a high comorbidity burden (coef: 0.09 (CI: 0.03

– 0.16) compared to patients with no comorbidity burden. After 12 month fol-

low up there was no association between comorbidity burden and HRQoL.

Conclusions:

After 3 month, patients with a high comorbidity burden gained

the most from a THA. The lack of association after 12 month may be a conse-

quence of the additional comorbid conditions having a stronger impact on the

patient reported HRQol.

No conflicts of interest reported

116.