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DOS Kongressen 2017 ·

211

Strength in soft tissue sarcoma patients after limb-

sparing surgery in the extremities – preliminary re-

sults

Casper Sæbye, Johnny Keller, Henning Andersen, Thomas Baad-Hansen

Department of Orthopaedic Surgery, Sarcoma Center at Aarhus University

Hospital, Aarhus, Denmark;

Background and purpose:

Only few studies have investigated strength in soft

tissue sarcoma patients by using objective measurements.

Purpose:

This study intends to determine the effects of limb-sparing surgery

on the functional outcome measured by strength at the first 3 months in soft

tissue sarcoma patients.

Methods:

Patients who underwent surgery for a soft tissue sarcoma in the

extremities at Aarhus University Hospital were included. Patients with dis-

seminated disease or patients who had undergone replacement surgery in the

disease-affected extremity were excluded. Patients completed a dynometric

muscle test with the Biodex System 3 dynamometer before surgery, 1 month

and 3 months after surgery on both the disease-affected and healthy side. The

results were compared to normative data. A percentage between the obtained

value compared to the expected value was calculated.

Results:

This study included 25 patients who completed pre-operative mea-

surement, while 13 patients completed 1 months and 3 months after surgery

measurement. There was no significant difference found between healthy and

disease-affected side pre-operatively and 3 months after surgery (p=0.57 and

p=0.10, respectively). However, 1 month after surgery the healthy side was

significantly stronger (p<0.01). Before surgery patients had a mean strength

on 78.96% of the expected (95%-CI: 72.11-85.81). 1 month after surgery,

they had a mean strength on 77.90% of the expected (95%-CI: 68.46-87.34).

While 3 months after surgery patients had a mean strength of 77.48% of the

expected (95%-CI: 65.46-89.49).

Conclusion:

We did not find any significant difference in function, measured

by the dynamometer, between the disease-affected side and the healthy side

after 3 months. However, soft-tissue sarcoma patients have significant reduced

strength when compared to healthy people.

No conflicts of interest reported

163.