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52

· DOS Abstracts

Minimal Important Change determined with a novel

method focusing on patients’ perspectives of important

change for the Oxford Knee Score and the Forgotten Joint

Score after knee replacement

Lina Holm Ingelsrud, Ewa Roos, Kirill Gromov, Henrik Husted, Berend Terluin, Anders

Troelsen

Department of Orthopaedic Surgery, Copenhagen University Hospital Hvidovre;

Department of Sports Science and Clinical Biomechanics, University of Southern

Denmark; Department of Orthopaedic Surgery, Copenhagen University Hospital

Hvidovre; Department of Orthopaedic Surgery, Copenhagen University Hospital

Hvidovre; Department of General Practice and Elderly Care Medicine, VU Univer-

sity Medical Center, Amsterdam; Department of Orthopaedic Surgery, Copenhagen

University Hospital Hvidovre

Background:

Interpreting changes in Oxford Knee Score (OKS) and Forgotten Joint

Score (FJS) after undergoing knee replacement is challenged by lack of method-

ologically rigorous methods to derive on Minimal Important Change (MIC) values.

Purpose / Aim of Study:

To determine MIC values for the OKS and FJS in patients

undergoing primary knee replacement in Denmark.

Materials and Methods:

Patients undergoing knee replacement between January

2015 and May 2016 were selected from one hospital’s arthroplasty database. OKS

and FJS were completed preoperatively and at 1 year postoperatively, accompanied

by a 7-point anchor question ranging from “better, an important improvement”

to “worse, an important worsening”. MIC improvement values were defined with

the predictive modelling approach based on logistic regression, with patients’ deci-

sions on important improvement as dependent variable and change in OKS/FJS as

independent variable. Furthermore, the MIC was adjusted for the high proportion

of improved patients.

Findings / Results:

We identified 341 patients with 1-year follow-up data, with

a mean age of 67.4 years (63% female). Complete data for OKS, FJS and anchor

questions were found for 307/341 patients (90%), and 85% (n=261) of these

patients were importantly improved. The Spearman’s correlation between the an-

chor and the change score was 0.59 for OKS, and 0.61 for FJS. Adjusted predictive

MIC values (95% CI) for improvement were 6.6 (4.6; 9.2) for OKS and 13.0 (8.4;

19.4) for FJS.

Conclusions:

The MIC value of 6.6 for OKS and 13.0 for FJS, determined with

novel MIC methodology, corresponds to minimal improvements that the average

patient finds important. These values may aid in evaluating the clinical relevance of

improvement after knee replacement surgery.

No conflicts of interest reported

4.