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· DOS Abstracts

Digitally reconstructed radiograph based

radiostereometric analysis: A novel method

validated on the hip joint

Sepp De Raedt, Lars Hansen, Peter Bo Jørgensen, Bjarne Mygind-Klavsen,

Maiken Stilling

Research and development, Nordisk Røntgen Teknik; Orthopedic Research

Unit, Department of Clinical Medicine, Aarhus University Hospital; Orthopedic

Research Unit, Department of Clinical Medicine, Aarhus University Hospital;

Department of Orthopedic Surgery, Aarhus University Hospital; Orthopedic

Research Unit, Department of Clinical Medicine, Aarhus University Hospital

Background:

Dynamic radiostereometric analysis (dRSA) can track 3D in-vivo

movements of bones or implants, but analysis is time consuming. Current mark-

er based RSA (MM) requires bone markers to be inserted and traditional model

based RSA (MBM) requires models to be manually matched on each radiograph.

We propose a novel digitally reconstructed radiograph based method (DRR) for

automated analysis of RSA recordings of the hip joint.

Purpose / Aim of Study:

To evaluate precision of DRR compared with MBM

(MM as gold standard).

Materials and Methods:

Seven human cadaveric hips were CT- scanned and

preprocessed for analysis. Tantalum beads were inserted in the femur and pelvis.

dRSA images were acquired at 5 fr/sec during flexion, adduction and internal

rotation. All images were analyzed by DRR, MBM and MM. Migrations were

calculated with respect to MM in 6 degrees of freedom. Precision was assessed

as systematic bias (mean difference) and random variation (Pitman’s test) with

respect to MM as gold standard.

Findings / Results:

In total 288 dRSA images were analyzed. Systematic bias

for MBM and DRR with respect to MM in translations (Δ<0.018mm) and rota-

tions (Δ<0.009°) were approximately zero and no difference between MBM

and DRR (p>0.46) was found. Random variation was lower (p<0.00) in all de-

grees of freedom for DRR compared to MBM. For the femur translations DRR

had 40% better (Δ0.07mm) precision, and for femur rotations DDR precision

was 60% better (Δ0.25°) compared to MBM. For the pelvis translations DRR

had 6 fold better (Δ0.40mm) precision, and for pelvis rotations DDR had 2 fold

better precision (Δ0.34°) compared to MBM.

Conclusions:

DRR is a novel method for analysis of dRSA and can be used clini-

cally for kinematic based diagnostic studies. It is automated, noninvasive, not

user-dependent and more precise in comparison with MBM for analysis of the

hip joint.

No conflicts of interest reported

137.