192
· DOS Abstracts
Efficacy of ultrasound-guided Saphenous and
Obturator Nerve Blocks after primary Knee
Arthroplasty. A double-blind, randomized clinical
study
Jens Bagger, Mette Hornsleth, Katja Lenz, Pia Therese Jaeger, Katrine Tanggaard,
Jens Børglum, Kenneth Jensen
Department of Orthopaedic Surgery, Copenhagen University Hospital Bispebjerg;
Department of Orthopaedic Surgery, Copenhagen University Hospital Bispebjerg;
Departement og Anestesiology, Copenhagen University Hospital Bispebjerg; Department
of Anestesiology HOC, Copenhagen University Hospital Rigshospitalet; Department of
Anestiosiology, Zeeland University Hospital, Roskilde; Department of Anestiosiology,
Zeeland University Hospital, Roskilde; Departement og Anestesiology, Copenhagen
University Hospital Bispebjerg
Background:
Pain treatment following TKA often combines systemic analgesic with pe-
ripheral nerve Blocks and local infiltration analgesia (LIA).
Purpose / Aim of Study:
Wee hypothezed that a single-shot, low-volumen saphenous
nerve block would improve pain and ambulation scores and reduce opioid consumption
compared with placebo Blocks without LIA, and that addition of an obturator (posterior
branch) nerve block would potentially confer additional benefits
Materials and Methods:
75 patients were randomized in a 1:1:1 ratio to either an
ultrasound-guided saphenous nerve block (S Group), a combined saphenous/obturator
nerve block (SO Group), or placebo Blocks using isotonic saline (P Group).The primary
outcome was pain at 45 degree passive flexion of the knee joint in the first 24 hours
after surgery. Secondary autcomes included pain at rest, morphine demand, nausea and
vomiting, ambulation scores, length of stay. The nerve Blocks was add-ons to a regimen
consisting of naproxem, gabapentin, zolpidem and morphine iv PCA.
Findings / Results:
74 patients were included. The S Group had less pain on movement
(p<0.001) compared to placebo. This was replicated in the SO Group (p<0.05). Pain at
rest and morphine demand was significantly reduced in the S Group in the first 6 hours,
but the SO Group was similar to the placebo Group. Althoug nonsignificant, patients were
discharged earlier in the active Groups (p=0.019 and p=0.154). There were no differ-
ence in ambulation between Groups. 28 patients had in- hospital complications, 9 of
which were severe (Pneumonia, opioid intox, GI bleeding)
Conclusions:
The addition of a low-volumen saphenous nerve block significantly re-
duced pain on movement, pain at rest and opioid demand after primary TKA, but failed to
offer benefits for ambulation and length of stay. The value of adding an obtorator block
remains questionable
No conflicts of interest reported
143.