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DOS Kongressen 2016 ·
231
Scand-Ankle – Effect of alcohol intervention
among acute ankle fracture surgery (RCT)
Julie W. M. Egholm, Bolette Pedersen, Kristian Oppedal, Jes Bruun Lauritzen,
Bjørn Madsen, Hanne Tønnesen
Orthopedic Dept, Hospital of Southern Jutland, University of Southern
Denmark; WHO-CC, Clin Health Promotion Centre, Bispebjerg-Frederiksberg
Hospita, University of Copenhagen; Alcohol and Drug Research Western Norway,
Stavanger University Hospital, Norway; Dept Orthopaedic Surgery, Bispebjerg-
Frederiksberg Hospital, University of Copenhagen; Dept Orthopaedic Surgery,
Hvidovre Hospital, University of Copenhagen; Clin Health Promotion Centre,
Dept Health Sciences, Lund University, Sweden
Background:
Patients with high alcohol consumption have increased risk of
postoperative complications. Preoperative alcohol cessation intervention has
been shown to halve the frequency of postoperative complications. However, it
still remains unexplored whether alcohol cessation during and after surgery has
an impact on the prevalence of postoperative complications.
Purpose / Aim of Study:
The aim of this study was to evaluate the effect of
a new gold standard program for alcohol cessation intervention in the peri- and
postoperative period.
Materials and Methods:
The present study is designed as a randomized clini-
cal multi-center study. A total number of 70 patients with an ankle fracture
witch requires osteosynthesis and a excessive alcohol intake were included and
randomly allocated to either standard care or a 6-weeks gold standard program
with the aim of alcohol abstinence peri- and postoperatively. The structured pa-
tient education program involved weekly intervention at the orthopedic outpa-
tient clinic. Furthermore, patients were provided with thiamine and B-vitamins,
prophylaxis and treatment for alcohol withdrawal symptom and disulfiram to
support abstinence. Biochemical validation of alcohol intake was done at the
weekly intervention meetings and follow-up visits after 6 weeks and 3, 6, 9
and 12 months. The main outcome measures were postoperative complications,
alcohol intake and cost-effectiveness.
Findings / Results:
The results on postoperative complications, alcohol con-
sumption and cost-effectiveness will be presented at the conference.
Conclusions:
The study will show if the 6-weeks gold standard program can
reduce postoperative complications after emergency surgery. The results will be
of relevance for the individual patient as well as for the society at large.
No conflicts of interest reported
182.