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· DOS Abstracts

Evaluation of Treatment of Bone Bridges After Injury

to the Growth Plate

Ahmed Abdul-Hussein Abood, Bjarne Møller-Madsen, Juan Manuel Shiguetomi-

Medina, Casper Bindzus Foldager, Ole Rahbek

Paediatric Ortopaedics, Aarhus University Hospital

Background:

Fractures involving the growth plate can cause bone bridge for-

mation leading to leg length discrepancy, angular bone deformities, and early

secondary arthrosis. The gold standard treatment is to remove the bone bridge

surgically and replace it with fat.

Purpose / Aim of Study:

The purpose was to evaluate bone bridge formation

using the gold standard compared with no treatment using MRI in a porcine

model.

Materials andMethods:

In five immature female pigs the distal femoral growth

plate was identified using fluoroscopy. The medial part of both growth plates

was injured in a standardised procedure using a 6 mm cannulated drill bit oper-

ated manually. The injury included the metaphyseal and epiphyseal part of the

bone to simulate a gap after excision of a bone bridge. The defects were rinsed

sterile saline. Defects in both hind legs were randomized to filling of subcutane-

ous fat (group A, n = 5) or no filling (group B, n = 5). The animals were followed

for 14 weeks. Three-dimensional MRI including water- content were performed

at 14 weeks and followed by euthanasia. Presence or absence of a bone bridge

was determined on MRI.

Findings / Results:

Bone bridge formation was confirmed in 60% of the ani-

mals for group A and 100% for group B. Water-content MRI shows less water-

content in the injured part of the growth plate compared to the uninjured all the

animals in both groups.

Conclusions:

Bone bridge formation was seen less frequently in the group

treated with the current gold standard, nevertheless a bone bridge still occurred

in 60% of the animals. Hence, there is a need for further investigation of alter-

native treatment options for bone bridge formation.

No conflicts of interest reported

35.